【BRP series】Full-automatic perfusion bioreactor system
Fermentation Tanks & Bioreactors
Lab Use
This series of equipment is used to cultivate suspension or microcarrier culture with different reaction capacities, and can be used for research, development and optimization of fermentation or cell culture processes, as well as the culture process of seed chain or small sample preparation.
Production Use
The stainless steel fermenters and bioreactors of Santa Jichen cover the range from pilot to production, and can be customized according to users requirements.
Made of firm components that conform to process standard, they are suitable for microbial and mammalian cell culture, and are easy to integrate with any process system.
Features
Contact design without dead ends;
Optimized process;
Modular design;
35-5000L (customization);
Stirring (top/bottom mounting);
Flexible configuration;
Conform to ASME, BPE and GAMP 5 guidelines;
Easy to operate and maintain;
PLC control system with HMI or SCADA;
Safe and secure
Materials
--parts in contact with medium: SS316L & Borosilicate Plass;
--Polishing degree:MP Ra≤0.6μm | EP Ra≤0.4μm (optional);
--SUS304 for parts not in contact with the material
Perfusion Cell Culture
Low shear centrifugal pumps
The cell suspension is pushed by the centrifugal pump to form a continuous circular flow. After entering the fibrous film, the waste liquid will be discharged out of the system through the film, and the cells will return into the culture system along with the loop.
HF-TFF Application
Cell bank
Seed expansion
--reducing the demand of bioreactors and scaling up across cascades
Perfusion
--increase VCD and productivity
Harvest
--trapping cells and reducing downstream pressure